This is what I hope happens on the last season of SV.
Lois says gosh, I'm a waste of human meat, and I wish to atone. I must devote the rest of my life to good works. What say you, cousin? Take my name and go out into the world as Lois Lane, intrepid girl reporter, for henceforth I shall be known as Sister John Wayne.
Clark realizes that Chloe is even more attractive when she calls herself Lois, and so the world's greatest love affair begins. (well second greatest, Clark's got his backdoor man, you know. In more ways than one....)